Ole Miss at South Carolina odds, picks and predictions

The Ole Miss Rebels (4-1, 0-1 SEC) meet the South Carolina Gamecocks (3-1, 1-1) on Saturday at Columbia. Kickoff at Williams-Brice Stadium is scheduled for 3:30 p.m. ET (ESPN). Let’s analyze the college football odds from BetMGM Sportsbook Ole Miss vs South Carolina oddsand make our college football picks and predictions.

Ole Miss fell from No. 5 to No. 11 US LBM Coaches Survey after a 20-17 home loss as a 15.5-point favorite against unranked Kentucky on Sept. 28. The loss was only Mississippi’s second loss since September 30, 2023. The Rebels were wiped out by the Wildcats, who controlled the football for 39 minutes and 43 seconds, while Ole Miss’ time of possession was 20 minutes and 17 seconds.

South Carolina enters this contest after a bye week. The Gamecocks probably needed it as they face a tough stretch of their schedule with back-to-back games against Ole Miss, No. 2 Alabama, No. 17 Oklahoma and No. 21 Texas A&M. The Gamecocks defeated Akron 50-7 as a 24.5-point home favorite in their last game (Sept. 21).

– Rankings: US LBM Coaches Survey conducted by the American Football Coaches Association and USA TODAY Sports

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Ole Miss at South Carolina odds

Powered by BetMGM Sportsbook; Visit the USA TODAY sports scores and sports betting hub for a complete list of college football odds. Lines were last updated at 6:20 a.m. ET.

• Money line: Ole Miss -350 (Bet $350 to Win $100) | South Carolina +260 (bet $100 to win $260)
• Against the Spread (ATS): Ole Miss -9.5 (-110) | South Carolina +9.5 (-110)
• Over/Under (O/U): 53.5 (O: -110 | U: -110)

Ole Miss at South Carolina picks and predictions

forecast

Ole Miss 27, South Carolina 19

Money line

No interest. HAPPEN.

Against the spread

USC is 3-1 ATS in its last four games as a home underdog.

Ole Miss lost to Kentucky, which defeated USC 31-6 on Sept. 7. Look for the Gamecocks to make enough devastating offensive plays and explosive plays on offense to keep this game interesting.

FanDuel Sportsbook offers a play with better value for the home team: Consider a play with a partial unit SOUTH CAROLINA +9.5 (-108).

Over/Under

The last two matches of this series yielded two overs and a total of 193. But be aware that the minor team will have better leverage in Saturday’s game.

Ole Miss has made a ton of plays in 5 games. Look for South Carolina, which has a lot of rushed plays, to slow things down.

Both sides did an excellent job of preventing 6-point shots in the red zone.

BACK BELOW 53.5 (-110).

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