The latest on Justin Herbert, Jorden Love, Joe Mixon and more

We are officially three weeks into the NFL season and the injuries continue to pile up. Los Angeles Chargers quarterback Justin Herbert left Sunday’s 20-10 loss to the Steelers with a severe ankle sprain, Packers signalman Jordan Love missed more playing time with a knee injury and San Francisco 49ers superstar Christian McCaffrey, remains on injured reserve with Achilles tendonitis.

Here is a list of the key players dealing with injuries and their current statuses heading into Week 4.

Quarterbacks

Jordan Love, Green Bay Packers

Status: Questionable vs. Vikings

Love sprained his MCL in the final seconds of Green Bay’s Week 1 loss to the Philadelphia Eagles. Backup QB Malik Willis has replaced him the last two weeks and led Green Bay to two wins against the Colts and Titans, respectively.

Love missed Week 3 and was able to practice on a limited basis this week.

Justin Herbert, Los Angeles Chargers

Status: Questionable vs. Chiefs

Herbert injured his right leg while trying to escape the pocket in the third quarter of the 26-3 win over the Carolina Panthers in Week 2. He left the field but returned to the game. In a loss to the Steelers in Week 3, he did not play the entire game. Herbert is questionable against Kansas City.

Tua Tagovailoa, Miami Dolphins

Status: Out, placed on injured reserve

Tagovailoa suffered at least the third concussion of his career in the 31-10 loss to the Buffalo Bills in Week 2. On September 17, Miami placed him on the injured reserve list and he will be out until at least Week 8 against the Arizona Cardinals on October 27.

Russell Wilson, Pittsburgh Steelers

Status: Out against Colts

Wilson has yet to play this season due to a calf injury. Head coach Mike Tomlin said Wilson (calf) will begin Week 4 preparations on Wednesday as a limited participant and the Steelers are preparing for Justin Fields to start at quarterback for the fourth consecutive game on Sunday against the Colts, Brooke Pryor reports from ESPN.com.

Running backs

Christian McCaffrey, San Francisco 49ers

Status: Out, placed on injured reserve

McCaffrey, arguably the NFL’s top offensive threat, was placed on injured reserve with an Achilles tendon injury and is expected to miss at least six weeks. Backup running back Jordan Mason has stepped up in his absence, averaging 4.8 yards per carry with 324 yards and two scores in three weeks.

Isiah Pacheco, Kansas City Chiefs

Status: Out, placed on injured reserve

Many thought this would be Pacheco’s breakout season, but unfortunately he will likely be out for at least six weeks with a broken fibula. With backup Clyde Edwards-Helaire also injured, the Chiefs signed Kareem Hunt to their practice squad. Carson Steele will be the primary defender in Week 4 against Los Angeles.

Joe Mixon, Houston Texans

Status: Questionable against Jaguars

Mixon suffered an ankle injury midway through the Texans’ 19-13 win over the Chicago Bears in Week 2, but he appears to have avoided a long-term injury. He missed Week 3 and was not seen at practice on Wednesday.

Kenneth Walker III, Seattle Seahawks

Status: Questionable vs. Lions

Walker is dealing with an oblique injury and missed Week 2 and Week 3. Zach Charbonnet has stepped in as the starter and has been productive. Last Sunday against Miami, he ran 18 times for 91 yards (5.1 average) and two scores.

Austin Ekeler, Washington Commander

Status: Out vs. Cardinals

Ekeler appeared to be on his way to a great performance against Cincinnati on Monday – 35 yards rushing and a score – but suffered a concussion in the first half. He was expelled from Washington on Wednesday.